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cruise to South America
Machu Picchu

San Diego Cruise Guide > Cruise Destinations > South America

Cruises from San Diego to South America

Two cruise lines offer cruises from San Diego to Incan and Mayan historic sites in South America and Central America. Choose a round-trip voyage or a one-way cruise to Chile, Argentina or Brazil. See the full schedule of departures below.

Lima (Peru) shore excursions include the Incan wonder of Machu Picchu. The city itself has beautiful historic buildings and excellent restaurants.

Puerto Chiapas (Mexico) is the Pacific gateway to the Mayan world. The port is the starting point for excursions to the ruins at Izapa. Closer to town you can explore a rainforest or shop for local crafts.

From Puerto Quetzal (Guatemala) a flight to Tikal reveals a famous Mayan archaeological site.

The historic quarter of Valparaiso (Chile) is a World Heritage Site. Ride a funicular up to take in views over the city and ocean. About two hours inland is Santiago, the capital of Chile.

Round-Trip Cruises from San Diego to South America

28-day cruise to South America on Holland America Line. Round-trip from San Diego to Cabo San Lucas (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Fuerte Amador (Panama), Trujillo (Peru), Lima (Peru), Manta (Ecuador), Puntarenas (Costa Rica), Corinto (Nicaragua), Puerto Quetzal (Guatemala), Manzanillo (Mexico), and Puerto Vallarta (Mexico).
• 2018 departure: February 25.

One-Way Cruises from San Diego to Chile, Argentina or Brazil

18-day cruise to Chile on Holland America Line. One-way from San Diego to Valparaiso (Chile). Visit Cabo San Lucas (Mexico), Acapulco (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), Manta (Ecuador), Salaverry (Peru), Callao (Peru) and Coquimbo (Chile).
• 2017 departure: September 28.

34-day cruise to Brazil on Holland America Line. One-way from San Diego to Rio de Janeiro (Brazil). Visit Cabo San Lucas (Mexico), Acapulco (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), Manta (Ecuador), Salaverry (Peru), Callao (Peru), Coquimbo (Chile), Valparaiso (Chile), Puerto Montt (Chile), Pisco (Peru), Strait of Magellan, Ushuaia (Argentina), Cape Horn, Stanley (Falkland Islands), Montevideo (Uruguay), Buenos Aires (Argentina), and Punta del Este (Uruguay).
• 2017 departure: September 28.

35-day cruise to Brazil on Oceania Cruises. One-way from San Diego to Rio de Janeiro (Brazil). Visit Puerto Vallarta (Mexico), Manzanillo (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puntarenas (Costa Rica), the Panama Canal, Curacao, Grenada, Trinidad & Tobago, Devil's Island (French Guiana), Santarem (Brazil), Parintins (Brazil), Manaus (Brazil), Boca Da Valeria (Brazil), Alter Do Chao (Brazil), the Amazon River, Fortaleza (Brazil), Recife (Brazil), and Salvador (Brazil).
• 2017 departure: December 16.

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Lima Peru
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